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CMA also plays a role in stem cell self-renewal and differentiation by influencing metabolic products in stem cells, promoting embryonic stem cell self-renewal with high activity, enhancing differentiation and maintaining embryonic stem cell viability through the mediation of pluripotency factors such as octamer-binding transcription factor 4 (OCT4) and SRY-box transcription factor 2 (SOX2) (97)
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Research from Diagen, the original patent holder of BPC-157, demonstrated that the arginate form resists gastric acid degradation far more effectively than the acetate form
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