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In contrast to the above studies in which GSH was shown to have its “classic” antioxidative and protective effect, investigation of the impact of overexpression of the mitochondrial GSH transporter OGC in NRK-52E cells on chemically induced cytotoxicity was extended to a clinically used drug, cisplatin (CDDP), that is known to have nephrotoxicity as a dose-limiting side effect [92]