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Histone Acetyltransferases (HATs) and Histone Deacetylases (HDACs) The level of histone acetylation is regulated by two families of enzymes: histone acetyltransferases (HATs) and histone deacetylases (HDACs)
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18 The increased production of hepcidin is positively associated with the elevated levels of circulating iron through the bone morphogenetic protein and hemojuvelin (BMP/HJV)-small mothers against decapentaplegic (SMAD) signaling pathway, and in sensing plasma transferrin levels through the hemochromatosis proteins (HFE) and transferrin receptor 2 (TFR2) complex, 27 , 28 indicating an intact physiological response to full iron stores
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