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Generally, these variation peptides are found in parts per million in active technologies that topical products claim to include at high percentages but the final concentration of the variation peptides in topical products is generally less than 0.01% and these peptides would then have to be converted to even smaller amounts of pure copper peptides within the skin

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National Library of Medicine Medical Subject Headings (MeSH) GPCR Cell Line Archived 3 April 2015 at the Wayback Machine "IUPHAR/BPS Guide to PHARMACOLOGY Database (GPCRs)"