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176 Given these pathophysiological insights, targeting both inflammation and oxidative stress mechanisms in digestive and extra-digestive GERD could offer promising new strategies for managing this chronic and challenging condition
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Similarly, resistance to oxidative attack increased after overexpression of GPX5 in CHO-K1 cells, and GPX5 overexpressing cells reduced lipid peroxidation levels and downstream DNA damage marker 8-OXODG levels compared to control cells (Taylor et al., 2013)
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