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There’s only one phase one trial that’s registered right now, and it’s been registered since 2016, and nothing has been updated on that registration, so that tells you something as well
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In murine models, NNMT knockdown did not induce the accumulation of NAM in livers and adipose tissues, nor did it cause significant alterations in the intracellular levels of NAD + in hepatocytes ( + is not necessary for this regulatory process
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