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MEGA-PRESS: enhanced specificity and original data Although PRESS has been demonstrated to detect GSH, its clinical application faces challenges due to the low cerebral concentration of GSH (1.5-3 mM), suboptimal signal-to-noise ratio in cerebral spectra, and significant spectral overlap between metabolite peaks of varying intensities (creatine, glutamate, glutamine, etc.) [208]

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Feb 14 2005;118(1-3):133-9