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What You Should Know Your body can’t make ergothioneine and must get it entirely through diet, mostly from mushrooms A dedicated transporter protein specifically moves ergothioneine to tissues most vulnerable to age-related damage Recent studies show it boosts NAD+ levels, improves exercise endurance, and protects cognitive function Studies link higher blood levels to 21% lower cardiovascular mortality and 50% reduced cognitive decline risk What is Ergothioneine

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Keywords: vitamin B-12, folic acid, folate, holotranscobalamin, homocysteine, methylmalonic acid, pernicious anemia Statement of Significance : There is significant circumstantial evidence that excess folic acid consumption exacerbates vitamin B-12 insufficiency, but a biochemical/physiological mechanism has not yet been identified