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Using mutants deprived of the N-terminal AcSDKP tetrapeptide, of the KLKKTET actin-binding sequence, and carrying a Lys16Ala point mutation, one study showed that increased intracellular expression of the peptide was sufficient to induce PAI-1 gene expression in endothelial cells and to stimulate expression and release of MMP-1, MMP-2, and MMP-3 [3]

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Topical application of GHK-Cu tripeptide complex for hair growth stimulation: Clinical and histological study

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