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By binding to AMY1R and AMY3R receptors in the hypothalamus and area postrema, cagrilintide suppresses appetite, slows gastric emptying, and reduces glucagon secretion (PMID 40609154)
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In addition to the categorization based on structural pathology, the condition is understood to arise from a complex interaction of biomechanical factors, such as degenerative changes, muscle imbalances, cumulative microtrauma, and psychosocial elements, including anxiety, depression, and maladaptive coping strategies [3,4,5]
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