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Notably, ferric citrate did not affect the chemiluminescence produced by human colonic mucosa, suggesting that there is sufficient free iron in inflamed biopsies already to drive the Fenton reaction maximally (98)

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Pain descriptors with high specificity for nociceptive pain include terms like “heavy, stinging, lacerating, and suffocating.” Although diagnosing nociceptive pain can be complex due to the potential presence of mixed pain components—nociceptive, neuropathic, and nociplastic—a definitive physical examination or diagnostic testing, such as imaging, can often identify a treatable source of pain (73–75)