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It progresses to form tender or deep-seated nodules, which expand and coalesce to form large painful abscesses
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These arguments demonstrate that models of the methionine cycle need to be examined in greater detail to determine if (i) GSH does indeed accumulate under vitamin B 12 deficiency, (ii) if it does, how does vitamin B 12 —deficiency induced hyperhomocysteinemia affect GSH levels
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