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However, the research was conducted solely on the Korean population whose metabolic characteristics related to BMI and T2DM could be different from those of other ethnicities, thus requiring further evaluations ( Metabolic dysfunction-associated steatotic liver disease (MASLD), and metabolic dysfunction-associated steatohepatitis (MASH) are common chronic liver conditions that often present with MetS

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Furthermore, the NADPH-producing metabolic enzyme ME1 which links glycolysis with the TCA cycle was reported to promote the metastatic potential of HCC and correlated with poor prognosis [102]