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Additionally, we performed widely accepted UPR assays to show that none of the UPR sensors, including IRE1α, PERK, and ATF6, were activated by erastin or cystine starvation in both cell types (Fig

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The exometabolomic and endometabolomic data can be obtained at the following link: The transcriptomic data can be obtained at the following link: Code availability All the scripts used for differential expression analysis and GSEA analysis can be obtained at the following link: All the scripts used for the in-silico fluxomics computation are available at: References Bray, F