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To determine which proteoforms may be associated with this categorical diagnosis, parallel linear models were fit with quantification ratio of each peptide as outcome variables, and diagnostic class, age at death, sex, post-mortem interval (hours) and number of years in education as explanatory variables
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Rather, the majority of orally ingested l-carnitine in mice produced a previously unappreciated intermediary metabolite, γ-butyrobetaine (γBB), in a gut microbiota–dependent step that occurred at a site anatomically proximal to, and at a rate 1,000-fold higher than the rate of the formation of TMA (26)
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